Basket Updated
0
Items added
Apoptosis is a type of programmed cell death that occurs normally throughout the lifespan and can also occur in response to harmful stimuli. Apoptotic cells are identified by their altered morphology, caspase activation, and the presence of damaged DNA.
Activated by pro-inflammatory signaling, ischemic injury or viral infection, necroptosis is a programmed regulated form of necrosis requiring RIP3 and MLKL
Necrosis has been classically defined as an unprogrammed form of cell death that occurs in response to overwhelming chemical or physical insult.
These markers can be used to study necroptosis and pyroptosis, forms of regulated necrotic cell death that share morphological features with necrosis.
Products and Related Resources for Cell Death and Viability SARS-CoV-2 Research
Regulation of cell death due to viral infection is important for host survival. In this series, we look at pathways regulated through cellular responses to viruses.
Here’s what you should know about your target before you start searching for antibodies, and the questions to ask to avoid choosing the wrong one.
Streamline your neurodegeneration therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Streamline your oncology therapeutic development with CST recombinant monoclonal antibodies, ELISA and cellular assay kits, custom products, and services.
Mutations in cell death pathways, such as apoptosis, mitophagy, necroptosis, and autophagy, contribute to neuronal cell death and the progression of neurodegenerative diseases.
Find out which epigenetic markers are important drivers in mixd lineage leukemia, or MLL.
Expert-reviewed interactive pathway providing a current overview of SAPK/JNK Signaling.
Epigenetic Drivers and Regulators of Cancer, epigenetics's role in cancer initiation & progression is critical for prevention, detection & treatment.
Learn to ChiP
Interactive p38 MAPK pathway. Learn how p38 MAPK is involved in regulation of HSP27, MAPKAPK-2, MAPKAPK-3, & several transcription factors.
Discover the most important epigenetic markers that contribute to the progression of diffuse intrinsic pontine glioma (DIPG).
Discover the epigenetic drivers that help drive MDS / AML cancers
Discover the key epigenetic drivers of breast cancer and the best products to target them.
Discover the top epigenetic markers that you should look out for in prostate cancer research.
Summary of human oncogenes and tumor suppressor genes sorted by signaling pathway.
The Akt Binding Partners Table provides a list of proteins that bind to Akt along with their effects, activities, and corresponding PubMed reference(s).
Expert-reviewed interactive pathway providing a current overview of Histone Methylation.
At AACR 2023, many presentations focused on topics including cancer immunology, CAR-T therapy, spatial biology, mRNA vaccines, and KRAS.
Alphabetical listing of protein, pathway, and antibody acronyms, curated by Cell Signaling Technology.
Cell viability is a measure of the proportion of live, healthy cells within a population. Assays to assess cell viability measure metabolic activity, ATP content, cell proliferation, or membrane integrity.
The PI3K / Akt Substrates Table provides a comprehensive list of demonstrated downstream targets of Akt phosphorylation.
The Histone Modification Table provides a referenced list of many known histone modifications, associated modifying enzymes, and proposed functions.
Kinase-disease associations table showing kinases, kinase groups, disease types, and the molecular biology basis for disease.