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| 製品# | サイズ | 数量 | 価格 | 在庫 |
|---|---|---|---|---|
| 64097T | 1 Kit (8 x 20 microliters) |
|
| Product Includes | Quantity | Applications | Reactivity | MW(kDa) | Isotype |
|---|---|---|---|---|---|
| Phospho-Na,K-ATPase α1 (Tyr10) (E1Y9C) Rabbit mAb 13566 | 20 µl |
|
H M | 100 | Rabbit IgG |
| Pan-Cadherin (28E12) Rabbit mAb 4073 | 20 µl |
|
H M R | 130-150 | Rabbit IgG |
| E-Cadherin (24E10) Rabbit mAb 3195 | 20 µl |
|
H M | 135 | Rabbit IgG |
| 4F2hc/SLC3A2 (D3F9D) XP® Rabbit mAb 47213 | 20 µl |
|
H | 75-120 | Rabbit IgG |
| Caveolin-1 (D46G3) XP® Rabbit mAb 3267 | 20 µl |
|
H M R Hm Mk B Dg | 21, 24 | Rabbit IgG |
| N-Cadherin (D4R1H) XP® Rabbit mAb 13116 | 20 µl |
|
H M | 140 | Rabbit IgG |
| ENPP1 (D37B7) Rabbit mAb 5342 | 20 µl |
|
H | 140 | Rabbit IgG |
| Anti-rabbit IgG, HRP-linked Antibody 7074 | 100 µl |
|
Rab | Goat | |
| Na,K-ATPase α1 (D4Y7E) Rabbit mAb 23565 | 20 µl |
|
H | 100 | Rabbit IgG |
製品情報
Monoclonal antibodies are produced by immunizing animals with synthetic peptides corresponding to residues surrounding Pro12 of human Na,K-ATPase α1, Pro780 of human E-cadherin, Arg526 of human N-cadherin, Val509 of human 4F2hc/CD98, Glu20 of human caveolin-1, Leu520 of human ENPP1, a conserved region of human N-, R-, E- and P-cadherin proteins, or a synthetic phosphopeptide corresponding to residues surrounding Tyr10 of human Na,K-ATPase α1 protein.
The Na,K-ATPase is an integral membrane heterodimer belonging to the P-type ATPase family. Phosphorylation of Na,K-ATPase at Tyr10 has been implicated in the regulation of enzyme activity in response to hormones and neurotransmitters (1). Cadherins are a superfamily of transmembrane glycoproteins that contain cadherin repeats of approximately 100 residues in their extracellular domain. Cadherins mediate calcium-dependent cell-cell adhesion and play critical roles in normal tissue development. The classic cadherin subfamily includes N-, P-, R-, B-, and E-cadherins, as well as about ten other members that are found in adherens junctions, a cellular structure near the apical surface of polarized epithelial cells (2). 4F2hc is a transmembrane protein that belongs to the solute carrier family. 4F2hc forms heterodimeric complexes with various amino acid transporters, such as LAT1 and LAT2, and regulates uptake of amino acids (3). The 21-24 kDa integral proteins, caveolins, are the principal structural components of the cholesterol/sphingolipid-enriched plasma membrane microdomain caveolae. Three members of the caveolin family (caveolin-1, -2, and -3) have been identified with different tissue distributions (4). Ectonucleotide pyrophosphatase-phosphodiesterase 1 (ENPP1) is a single-pass, type II transmembrane protein primarily involved in ATP hydrolysis at the plasma membrane. ENPP1 plays important roles in bone mineralization and soft tissue calcification (5).
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